Mesosfini is located between the villages of Mournia and Prinia. It starts one kilometre outside Mournia and although it is initially narrow, it opens and forms long descents. It is one of the few known gorges in Crete that feature two long consecutive descents (70m and 80m).

It is a beautiful gorge with very interesting formations, like smooth rocks sculpted by the water, stalagmites in the big waterfalls and huge boulders on its bed. Mesosfini collects water from the Kato Kampos plateau, which lies between the Sachos (709m), Aggelomandra (689m) and Skylies (725m) peaks. It exits into the Voidomatos beach.